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Article

Conservation of hotspots for recombination in low-copy repeats associated with the NF1 microdeletion.

Nature genetics - 1 Dec 2006

Raedt Thomas De, Stephens Matthew, Heyns Ine, Brems Hilde, Thijs Daisy, Messiaen Ludwine, Stephens Karen, Lazaro Conxi, Wimmer Katharina, Kehrer-Sawatzki Hildegard, Vidaud Dominique, Kluwe Lan, Marynen Peter, Legius Eric

Abstract excerpt

Several large-scale studies of human genetic variation have provided insights into processes such as recombination that have shaped human diversity. However, regions such as low-copy repeats (LCRs) have proven difficult to characterize, hindering efforts to understand the processes operating in these regions. We present a detailed study of genetic variation and underlying recombination processes in two copies of...

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PMID: 17115058
DOI: 10.1038/ng1920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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