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Article

Altered expressions of the noncoding hsromega gene enhances poly-Q-induced neurotoxicity in Drosophila.

RNA biology - 1 Jan 2000

Sengupta Sonali, Lakhotia S C

Abstract excerpt

In an earlier report two P-transposon insertion alleles of the noncoding hsromega gene, hsromega(05241) and P292 were shown to enhance neurodegeneration caused by expression of ataxin-1 protein with expanded poly-Q in a Drosophila model. In present study, we examined the possible relation between hsromega gene expression and toxicity due to poly-Q pathogenesis. The Drosophila hsromega gene produces several...

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PMID: 17114940
DOI: 10.4161/rna.3.1.2559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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