Article
Backward genotype-trait association (BGTA)-based dissection of complex traits in case-control designs.
Human heredity - 1 Jan 2006
Zheng Tian, Wang Hui, Lo Shaw-Hwa
Abstract excerpt
BACKGROUND: The studies of complex traits project new challenges to current methods that evaluate association between genotypes and a specific trait. Consideration of possible interactions among loci leads to overwhelming dimensions that cannot be handled using current statistical methods. METHODS: In this article, we evaluate a multi-marker screening algorithm--the backward genotype-trait association (BGTA)...
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