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Article

NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.

Molecular cancer research : MCR - 1 Nov 2006

Kinsey Michelle, Smith Richard, Lessnick Stephen L

Abstract excerpt

A number of solid tumors, such as alveolar rhabdomyosarcoma, synovial sarcoma, and myxoid liposarcoma, are associated with recurrent translocation events that encode fusion proteins. Ewing's sarcoma is a pediatric tumor that serves as a prototype for this tumor class. Ewing's sarcomas usually harbor the (11;22)(q24;q12) translocation. The t(11;22) encodes the EWS/FLI fusion oncoprotein. EWS/FLI functions as an...

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Share to DAX-1 Orphan Nuclear Receptor
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Protein c-fli-1

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Source

Identifiers

PMID: 17114343
DOI: 10.1158/1541-7786.MCR-06-0090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.PMID 17114343Read ↗

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