Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma.

Cell cycle (Georgetown, Tex.) - 1 Sept 2006

Owen Leah A, Lessnick Stephen L

Abstract excerpt

Ewing's sarcoma is the second most common tumor of bone in children and young adults, and requires highly intensive chemotherapy along with surgery and/or radiation for successful treatment. Because these therapies are associated with significant short- and long-term side effects, new therapeutic approaches are needed. Most cases of Ewing's sarcoma contain somatic translocations between chromosomes 11 and 22 that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 22

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Protein c-fli-1

Share to RNA-Binding Protein EWS

Share to RNA Interference

Share to Sarcoma, Ewing

Share to Zebrafish Proteins

Source

Identifiers

PMID: 16969112
DOI: 10.4161/cc.5.18.3213

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma.PMID 16969112Read ↗

NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma.Semantic proximity Read ↗

EWS/FLI1 Target Genes and Therapeutic Opportunities in Ewing SarcomaSemantic proximity Read ↗

Ewing's Sarcoma Oncoprotein EWS–FLI1: The Perfect Target Without a Therapeutic AgentSemantic proximity Read ↗

Recent advances in the molecular pathogenesis of Ewing's sarcoma.Semantic proximity Read ↗

A Molecular Function Map of Ewing's SarcomaSemantic proximity Read ↗

EWS-FLI1 and Ewing's sarcoma: recent molecular data and new insights.Semantic proximity Read ↗

EWS/FLI1 Characterization, Activation, Repression, Target Genes and Therapeutic Opportunities in Ewing SarcomaSemantic proximity Read ↗

Ewing tumor biology: perspectives for innovative treatment approaches.Semantic proximity Read ↗

Targeting of EWS/FLI-1 by RNA interference attenuates the tumor phenotype of Ewing's sarcoma cells in vitro.Semantic proximity Read ↗

Ewing Sarcoma: Biology-Based Therapeutic PerspectivesSemantic proximity Read ↗

Regulation of EWSR1-FLI1 Function by Post-Transcriptional and Post-Translational ModificationsSemantic proximity Read ↗

Ewing sarcoma fusion oncogene: At the crossroads of transcription and DNA damage responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.