Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of alveolar type II cell differentiation in embryonic tracheal epithelium in mesenchyme-free culture.

Development (Cambridge, England) - 1 Apr 1999

Shannon J M, Gebb S A, Nielsen L D

Abstract excerpt

We have previously shown that fetal lung mesenchyme can reprogram embryonic rat tracheal epithelium to express a distal lung phenotype. We have also demonstrated that embryonic rat lung epithelium can be induced to proliferate and differentiate in the absence of lung mesenchyme. In the present study we used a complex growth medium to induce proliferation and distal lung epithelial differentiation in embryonic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Culture Media
Share to Cyclic AMP
Share to Epithelium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblast Growth Factor 10

Share to Fibroblast Growth Factors

Share to Growth Substances

Share to Mesoderm

Share to Trachea

Source

Identifiers

PMID: 10079230
DOI: 10.1242/dev.126.8.1675

Genes

FGF7
FGF1
FGF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of alveolar type II cell differentiation in embryonic tracheal epithelium in mesenchyme-free culture.PMID 10079230Read ↗

BMP4 modulates fibroblast growth factor-mediated induction of proximal and distal lung differentiation in mouse embryonic tracheal epithelium in mesenchyme-free culture.Semantic proximity Read ↗

The differentiation of distal lung epithelium from embryonic stem cells.Semantic proximity Read ↗

Chondroitin sulfate proteoglycans are required for lung growth and morphogenesis in vitro.Semantic proximity Read ↗

Mesenchymal maintenance of distal epithelial cell phenotype during late fetal lung development.Semantic proximity Read ↗

Derivation of Distal Lung Epithelial Progenitors from Murine Embryonic Stem Cells Using a Novel Three‐Step Differentiation ProtocolSemantic proximity Read ↗

Extracellular matrix-driven alveolar epithelial cell differentiation in vitro.Semantic proximity Read ↗

Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative populationSemantic proximity Read ↗

Discordant roles for FGF ligands in lung branching morphogenesis between human and mouseSemantic proximity Read ↗

Successful Establishment of Primary Type II Alveolar Epithelium with 3D Organotypic Coculture.Semantic proximity Read ↗

Determination of alveolar epithelial cell phenotypes in fetal sheep: evidence for the involvement of basal lung expansion.Semantic proximity Read ↗

Formation of Cysts by Alveolar Type II Cells in Three-dimensional Culture Reveals a Novel Mechanism for Epithelial MorphogenesisSemantic proximity Read ↗

FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.