Article
BMP4 modulates fibroblast growth factor-mediated induction of proximal and distal lung differentiation in mouse embryonic tracheal epithelium in mesenchyme-free culture.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2002
Hyatt Brian A, Shangguan Xiaofei, Shannon John M
Abstract excerpt
Lung morphogenesis and differentiation require interaction between the epithelium and mesenchyme, which is mediated by diffusible molecules such as fibroblast growth factors (FGFs), bone morphogenetic protein 4 (BMP4), and Shh. We have used mesenchyme-free culture to study the effects of these molecules on lung epithelial differentiation. We have tested the individual abilities of FGF1, FGF2, FGF7, FGF9, FGF10,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.