Article
The differentiation of distal lung epithelium from embryonic stem cells.
Current protocols in stem cell biology - 1 Jul 2007
Van Vranken Benjamin E, Rippon Helen J, Samadikuchaksaraei Ali, Trounson Alan O, Bishop Anne E
Abstract excerpt
The potential for embryonic stem (ES) cells to differentiate into cells with a distal lung epithelial phenotype has been demonstrated using different in vitro culture methods. Three separate protocols are described here that utilize both murine and human ES cells. The distal lung epithelial phenotype is induced through the use of embryonic distal lung mesenchyme in coculture systems with differentiating embryoid...
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