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Article

Ancestry- and Age-Dependent Effects of NOS3 Polymorphisms on Coronary Heart Disease Risk: A Meta-analysis.

Cardiovascular toxicology - 1 Oct 2025

Jafarinejad-Farsangi Saeideh, Asgarian Sara, Ghahari Sara, Najd-Hassan-Bonab Leila, Moazzam-Jazi Maryam

Abstract excerpt

The relevance of NOS3 common polymorphisms to coronary heart disease (CHD) risk is inconsistent among different studies, and little is known about the contribution of the genetic variants to the disease development across ancestries and age groups. To address this, we performed a comprehensive meta-analysis stratified by age and ancestry, including 123 eligible studies (29,040 cases and 26,694 controls). Random-...

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Identifiers

PMID: 40758197
DOI: 10.1007/s12012-025-10050-2

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NOS3

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