Article
[Association between polymorphism of Matrilin-1 gene (MATN1) with susceptibility to adolescent idiopathic scoliosis].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Sept 2009
Chen Zhi-jun, Qiu Yong, Yu Yang, Wang Bin, Zhu Ze-zhang
Abstract excerpt
OBJECTIVE: To investigate the association of matrilin-1 gene polymorphisms with adolescent idiopathic scoliosis (AIS) risk. METHODS: This study population consisted of 419 patients with AIS and 460 healthy controls. The maximum Cobb angle of AIS patients was recorded. For initial screening, the 7 tagSNPs were genotyped in 197 cases and 172 controls. Next, we validated any significant associations in additional...
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