Article
Biochemical basis of a novel T lymphocyte receptor immunodeficiency by immunohistochemistry. A possible CD3 gamma abnormality.
Laboratory investigation; a journal of technical methods and pathology - 1 May 1991
Arnaiz-Villena A, Perez-Aciego P, Ballestin C, Sotelo T, Perez-Seoane C, Martin-Villa J M, Regueiro J R
Abstract excerpt
Necropsic lymphoid tissues obtained from an infant with a novel type of immunodeficiency consisting of a peripheral blood T lymphocyte antigen receptor (TCR) surface expression defect, were analyzed by immunohistochemistry for the expression of various TCR-associated epitopes. The work was aimed...
Topics
- Antibodies, Monoclonal
- Antigens, Differentiation, T-Lymphocyte
- CD3 Complex
- Epitopes
- Humans
- Immune System Diseases
- Immunohistochemistry
- Infant
- Liver
- Lymph Nodes
- Male
- Phenotype
- Receptors, Antigen, T-Cell
- Spleen
- Thymus Gland