Article
Freshly isolated Thy-1+ dendritic epidermal cells express T cell receptor gamma delta-CD3.
Journal of dermatological science - 1 Nov 1990
Shimada S, Caughman S W, Bluestone J A, Cron R Q, Owen F L, Smith J A, Katz S I
Abstract excerpt
Within murine epidermis exists a population of Thy-1+ DEC which express membrane Thy-1 antigen, but lack CD8 or CD4 antigen. We examined freshly obtained non-cultured Thy-1+ DEC both by immunofluorescence and by biochemical techniques to identify the protein products of the T cell receptor (TCR) and the associated CD3 complex on these cells. Virtually all of the Thy-1+ DEC are brightly positive in CD3 expression...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Surface
- CD3 Complex
- CD4 Antigens
- CD8 Antigens
- Dendritic Cells
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data