Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.

Journal of psychopharmacology (Oxford, England) - 1 Sept 2007

Hwang Rudi, Shinkai Takahiro, De Luca Vincenzo, Ni Xingqun, Potkin Steven G, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L

Abstract excerpt

Dopamine D1 receptors (D1) in the prefrontal cortex have been implicated in the modulation of cognitive processes as well as both positive and negative symptoms of schizophrenia. Therefore pharmacologic agents with potent D1 effects such as clozapine may influence the symptoms of schizophrenia (S...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antipsychotic Agents
Share to Black or African American
Share to Clozapine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Forecasting

Share to Prefrontal Cortex

Share to Receptors, Dopamine D1

Share to Schizophrenia

Share to White People

Source

Identifiers

PMID: 17092969
DOI: 10.1177/0269881106072341

Genes

DRD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17092969-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association study of four dopamine D1 receptor gene polymorphisms and clozapine treatment response.PMID 17092969Read ↗

Association study of 12 polymorphisms spanning the dopamine D(2) receptor gene and clozapine treatment response in two treatment refractory/intolerant populations.Semantic proximity Read ↗

Dopamine D4 and D5 receptor gene variant effects on clozapine response in schizophrenia: replication and exploration.Semantic proximity Read ↗

Dopamine D2 receptor gene variants and quantitative measures of positive and negative symptom response following clozapine treatment.Semantic proximity Read ↗

Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response.Semantic proximity Read ↗

Meta-analysis of dopamine receptor D1 rs4532 polymorphism and susceptibility to antipsychotic treatment response.Semantic proximity Read ↗

D2 receptor genetic variation and clinical response to antipsychotic drug treatment: a meta-analysis.Semantic proximity Read ↗

Dopamine D4 receptor gene polymorphisms: relation to ethnicity, no association with schizophrenia and response to clozapine in Israeli subjects.Semantic proximity Read ↗

Clinical response to antipsychotic drug treatment: association study of polymorphisms in six candidate genes.Semantic proximity Read ↗

Lack of association between a polymorphism in the promoter region of the dopamine-2 receptor gene and clozapine responseSemantic proximity Read ↗

Effect of dopamine D3 receptor gene polymorphisms and clozapine treatment response: exploratory analysis of nine polymorphisms and meta-analysis of the Ser9Gly variant.Semantic proximity Read ↗

Pharmacogenetics of clozapine treatment response and side-effects in schizophrenia: an updateSemantic proximity Read ↗

Allelic variation in the D4 dopamine receptor (DRD4) gene does not predict response to clozapine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.