Article
Association of SARS susceptibility with single nucleic acid polymorphisms of OAS1 and MxA genes: a case-control study.
BMC infectious diseases - 6 Jul 2006
He Jing, Feng Dan, de Vlas Sake J, Wang Hongwei, Fontanet Arnaud, Zhang Panhe, Plancoulaine Sabine, Tang Fang, Zhan Lin, Yang Hong, Wang Tianbao, Richardus Jan H, Habbema J Dik F, Cao Wuchun
Abstract excerpt
BACKGROUND: Host genetic factors may play a role in susceptibility and resistance to SARS associated coronavirus (SARS-CoV) infection. The study was carried out to investigate the association between the genetic polymorphisms of 2',5'-oligoadenylate synthetase 1 (OAS1) gene as well as myxovirus resistance 1 (MxA) gene and susceptibility to SARS in Chinese Han population. METHODS: A hospital-based case-control...
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