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Article

Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?

Journal of medical genetics - 1 Feb 2006

Tessier M-C, Qu H-Q, Fréchette R, Bacot F, Grabs R, Taback S P, Lawson M L, Kirsch S E, Hudson T J, Polychronakos C

Abstract excerpt

BACKGROUND: The 2',5'-oligoadenylate synthetase genes (OAS1, OAS2, and OAS3) map to human chromosome 12q24 and encode a family of enzymes pivotal to innate antiviral defence. Recently, the minor allele of an OAS1 single nucleotide polymorphism (SNP) that alters splicing (rs10774671) was found to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

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Source

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Identifiers

PMID: 16014697
DOI: 10.1136/jmg.2005.035212
PMCID: PMC2564627

Genes

OAS1
OAS2
OAS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16014697-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Type 1 diabetes and the OAS gene cluster: association with splicing polymorphism or haplotype?PMID 16014697Read ↗

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