Article
The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII.
Journal of leukocyte biology - 1 Jun 1991
Fleit H B, Kobasiuk C D
Abstract excerpt
THP-1 cells are a monocyte-like cell line derived from a patient with acute monocytic leukemia and unlike other leukemic cell lines has a normal diploid karyotype. We have characterized Fc gamma R expression on this cell line by flow cytometry, radiolabeled IgG1 and monoclonal antibody (mAb) binding assays, and biochemical analysis. Flow cytometric analysis of THP-1 cells with anti-Fc gamma RI, II, and III mAb,...
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