The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII.

doi:10.1002/jlb.49.6.556

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Article

The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII.

Journal of leukocyte biology - 1 Jun 1991

Fleit H B, Kobasiuk C D

Abstract excerpt

THP-1 cells are a monocyte-like cell line derived from a patient with acute monocytic leukemia and unlike other leukemic cell lines has a normal diploid karyotype. We have characterized Fc gamma R expression on this cell line by flow cytometry, radiolabeled IgG1 and monoclonal antibody (mAb) bind...

Topics

Antibodies, Monoclonal
Antigen-Antibody Complex
Antigens, Differentiation, Myelomonocytic
Calcitriol
Cell Line
Cytokines
Electrophoresis, Polyacrylamide Gel
Flow Cytometry
Fluorescent Antibody Technique
Gene Expression Regulation
Humans
Immunoglobulin G
Interferon-gamma
Leukemia, Monocytic, Acute
Lipopolysaccharide Receptors
Monocytes
Phenotype
Receptors, Fc

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Identifiers

PMID: 1709200
DOI: 10.1002/jlb.49.6.556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1709200-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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