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Article

Folate receptor-β constitutes a marker for human proinflammatory monocytes.

Journal of leukocyte biology - 1 Oct 2014

Shen Jiayin, Hilgenbrink Andrew R, Xia Wei, Feng Yang, Dimitrov Dimiter S, Lockwood Michael B, Amato Robert J, Low Philip S

Abstract excerpt

Activated macrophages are commonly involved in the pathogenesis of inflammatory and autoimmune diseases and have been frequently reported to overexpress FR-β. Although FR-targeted therapies aimed at eliminating activated macrophages have shown promise for treating inflammatory diseases, little work has been performed to evaluate whether other hematopoietic cells might also express FR-β. Analysis of peripheral...

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Identifiers

PMID: 25015955
DOI: 10.1189/jlb.2AB0713-372R
PMCID: PMC4163630

Genes

CCR2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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