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Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species.

BMC genomics - 14 Feb 2024

Adeola Adeniyi C, Bello Semiu F, Abdussamad Abdussamad M, Adedokun Rahamon A M, Olaogun Sunday C, Abdullahi Nasiru, Mark Akanbi I, Onoja Anyebe B, Sanke Oscar J, Mangbon Godwin F, Ibrahim Jebi, Dawuda Philip M, Salako Adebowale E, Kdidi Samia, Yahyaoui Mohamed Habib

Abstract excerpt

BACKGROUND: Prion diseases, also known as transmissible spongiform encephalopathies (TSEs) remain one of the deleterious disorders, which have affected several animal species. Polymorphism of the prion protein (PRNP) gene majorly determines the susceptibility of animals to TSEs. However, only limited studies have examined the variation in PRNP gene in different Nigerian livestock species. Thus, this study aimed...

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Identifiers

PMID: 38355406
DOI: 10.1186/s12864-024-10070-2
PMCID: PMC10865551

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Source receipt: pubmed, retrieved 7 Sept 2026.

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