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Article

Prion gene sequence variation within diverse groups of U.S. sheep, beef cattle, and deer.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2003

Heaton Michael P, Leymaster Kreg A, Freking Brad A, Hawk Deedra A, Smith Timothy P L, Keele John W, Snelling Warren M, Fox James M, Chitko-McKown Carol G, Laegreid William W

Abstract excerpt

Prions are proteins that play a central role in transmissible spongiform encephalopathies in a variety of mammals. Among the most notable prion disorders in ungulates are scrapie in sheep, bovine spongiform encephalopathy in cattle, and chronic wasting disease in deer. Single nucleotide polymorphisms in the sheep prion gene ( PRNP) have been correlated with susceptibility to natural scrapie in some populations....

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Identifiers

PMID: 14722726
DOI: 10.1007/s00335-003-2283-y

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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