Article
Evidence that accumulation of mutants in a biofilm reflects natural selection rather than stress-induced adaptive mutation.
Applied and environmental microbiology - 1 Jan 2007
Banas Jeffrey A, Miller Justin D, Fuschino Meghan E, Hazlett Karsten R O, Toyofuku Wendy, Porter Kristen A, Reutzel Sarah B, Florczyk Matthew A, McDonough Kathleen A, Michalek Suzanne M
Abstract excerpt
The accumulation of mutant genotypes within a biofilm evokes the controversy over whether the biofilm environment induces adaptive mutation or whether the accumulation can be explained by natural selection. A comparison of the virulence of two strains of the dental pathogen Streptococcus mutans s...
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