Article
Deficiency of BrpA in Streptococcus mutans reduces virulence in rat caries model.
Molecular oral microbiology - 1 Oct 2018
Wen Zezhang T, Scott-Anne Kathleen, Liao Sumei, De Arpan, Luo Meng, Kovacs Christopher, Narvaez Brendaliz S, Faustoferri Roberta C, Yu Qingzhao, Taylor Christopher M, Quivey Robert G
Abstract excerpt
Our recent studies have shown that BrpA in Streptococcus mutans plays a critical role in cell envelope biogenesis, stress responses, and biofilm formation. In this study, a 10-species consortium was used to assess how BrpA deficiency influences the establishment, persistence, and competitiveness of S. mutans during growth in a community under conditions typical of the oral cavity. Results showed that, like the...
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