Article
Spontaneous mutations in the flhD operon generate motility heterogeneity in Escherichia coli biofilm.
BMC microbiology - 8 Nov 2016
Horne Shelley M, Sayler Joseph, Scarberry Nicholas, Schroeder Meredith, Lynnes Ty, Prüß Birgit M
Abstract excerpt
BACKGROUND: Heterogeneity and niche adaptation in bacterial biofilm involve changes to the genetic makeup of the bacteria and gene expression control. We hypothesized that i) spontaneous mutations in the flhD operon can either increase or decrease motility and that ii) the resulting motility heterogeneity in the biofilm might lead to a long-term increase in biofilm biomass. RESULTS: We allowed the highly motile...
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