Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of Mahogunin Ring Finger-1 expression in mice.

Pigment cell research - 1 Dec 2006

Bagher Pooneh, Jiao Jian, Owen Smith C, Cota Christina D, Gunn Teresa M

Abstract excerpt

Mutations in mouse Mahogunin Ring Finger-1 (Mgrn1) were first recognized for their effect on agouti-mediated pigment-type switching. Mgrn1 null mutants are completely black and develop spongiform degeneration of the brain. Mgrn1 hypomorphs have dark fur but do not develop neurodegeneration. We characterized a new Mgrn1 hypomorphic allele caused by a gene-trap insertion. Mice homozygous for this mutation are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Melanocytes
Share to Mice, Inbred C3H
Share to Mice, Transgenic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pigments, Biological

Share to Protein Isoforms

Share to Skin Pigmentation

Share to Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 17083490
DOI: 10.1111/j.1600-0749.2006.00340.x

Genes

MGRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of Mahogunin Ring Finger-1 expression in mice.PMID 17083490Read ↗

Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.Semantic proximity Read ↗

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein.Semantic proximity Read ↗

Genetic studies of the mouse mutations mahogany and mahoganoid.Semantic proximity Read ↗

Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein.Semantic proximity Read ↗

Molecular and phenotypic analysis of Attractin mutant mice.Semantic proximity Read ↗

The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity.Semantic proximity Read ↗

Accessory proteins for melanocortin signaling: attractin and mahogunin.Semantic proximity Read ↗

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain proteinSemantic proximity Read ↗

Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus.Semantic proximity Read ↗

Genetic and phenotypic studies of the dark-like mutant mouse.Semantic proximity Read ↗

Melanism in peromyscus is caused by independent mutations in agouti.Semantic proximity Read ↗

The mouse mahogany locus encodes a transmembrane form of human attractin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.