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Article

The mouse mahogany locus encodes a transmembrane form of human attractin.

Nature - 11 Mar 1999

Gunn T M, Miller K A, He L, Hyman R W, Davis R W, Azarani A, Schlossman S F, Duke-Cohan J S, Barsh G S

Abstract excerpt

Agouti protein and agouti-related protein are homologous paracrine signalling molecules that normally regulate hair colour and body weight, respectively, by antagonizing signalling through melanocortin receptors. Expression of Agouti is normally limited to the skin, but rare alleles from which Ag...

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PMID: 10086356
DOI: 10.1038/18217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10086356-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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The mouse mahogany locus encodes a transmembrane form of human attractin.PMID 10086356Read ↗

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Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein.Semantic proximity Read ↗

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The mahogany mouse mutation: further links between pigmentation, obesity and the immune system.Semantic proximity Read ↗

Genetic studies of the mouse mutations mahogany and mahoganoid.Semantic proximity Read ↗

Molecular and phenotypic analysis of Attractin mutant mice.Semantic proximity Read ↗

Attractin/mahogany/zitter plays a critical role in myelination of the central nervous system.Semantic proximity Read ↗

Genetic analysis of attractin homologs.Semantic proximity Read ↗

Mice with mutations in the mahogany gene Atrn have cerebral spongiform changes.Semantic proximity Read ↗

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein.Semantic proximity Read ↗

Attractin: cautionary tales for therapeutic intervention in molecules with pleiotropic functionality.Semantic proximity Read ↗

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