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Article

Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2006

Cota Christina D, Bagher Pooneh, Pelc Piotr, Smith C Owen, Bodner Christina R, Gunn Teresa M

Abstract excerpt

Mahogunin Ring Finger 1 (Mgrn1) encodes a RING-containing protein with ubiquitin ligase activity that has been implicated in pigment-type switching. In addition to having dark fur, mice lacking MGRN1 develop adult-onset spongy degeneration of the central nervous system and have reduced embryonic...

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Source

Identifiers

PMID: 17075880
DOI: 10.1002/dvdy.20992

Genes

MGRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17075880-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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