Article
Genetic studies of the mouse mutations mahogany and mahoganoid.
Genetics - 1 Aug 1997
Miller K A, Gunn T M, Carrasquillo M M, Lamoreux M L, Galbraith D B, Barsh G S
Abstract excerpt
The mouse mutations mahogany (mg) and mahoganoid (md) are negative modifiers of the Agouti coat color gene, which encodes a paracrine signaling molecule that induces a swithc in melanin synthesis from eumelanin to pheomelanin. Animals mutant for md or mg synthesize very little or no pheomelanin d...
Topics
- Adrenocorticotropic Hormone
- Agouti Signaling Protein
- Animals
- Crosses, Genetic
- Female
- Hair Color
- Intercellular Signaling Peptides and Proteins
- Male
- Melanins
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mutation
- Obesity
- Phenotype
- Protein Biosynthesis
- Proteins