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Article

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein.

The Journal of clinical investigation - 1 Nov 2002

Phan Loan K, Lin Feng, LeDuc Charles A, Chung Wendy K, Leibel Rudolph L

Abstract excerpt

The mouse coat color mutant mahoganoid (md) darkens coat color and decreases the obesity of A(y) mice that ectopically overexpress agouti-signaling protein. The phenotypic effects of md are similar to those of the recently identified coat color mutant mahogany (Atrn(mg)). We report the positional cloning of mahoganoid, encoding a novel 494-amino acid protein containing a C3HC4 RING (really interesting new gene)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12438443
DOI: 10.1172/JCI16131
PMCID: PMC151815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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