Article

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein

2002-11-15

Abstract excerpt

The mouse coat color mutant mahoganoid (md) darkens coat color and decreases the obesity of A y mice that ectopically overexpress agouti-signaling protein.The phenotypic effects of md are similar to those of the recently identified coat color mutant mahogany (Atrn mg ).We report the positional cloning of mahoganoid, encoding a novel 494-amino acid protein containing a C3HC4 RING (really interesting new gene) domai...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ba3c4139-25d7-532b-94d0-78c696a64789
DOI: 10.1172/jci0216131

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain proteinDOI 10.1172/jci0216131Read

The mouse mahoganoid coat color mutation disrupts a novel C3HC4 RING domain protein.Semantic proximity Read

Genetic studies of the mouse mutations mahogany and mahoganoid.Semantic proximity Read

The mahoganoid mutation (Mgrn1md) improves insulin sensitivity in mice with mutations in the melanocortin signaling pathway independently of effects on adiposity.Semantic proximity Read

Spongiform degeneration in mahoganoid mutant mice.Semantic proximity Read

Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein.Semantic proximity Read

The mouse mahogany locus encodes a transmembrane form of human attractin.Semantic proximity Read

Mice with mutations in the mahogany gene Atrn have cerebral spongiform changes.Semantic proximity Read

New Zealand Ginger mouse: novel model that associates the tyrp1b pigmentation gene locus with regulation of lean body mass.Semantic proximity Read

Mahogany/attractin: en route from phenotype to function.Semantic proximity Read

Characterization of Mahogunin Ring Finger-1 expression in mice.Semantic proximity Read

Molecular and phenotypic analysis of Attractin mutant mice.Semantic proximity Read

Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function.Semantic proximity Read