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Article

Inducible nitric oxide synthase haplotype associated with hypertension and responsiveness to antihypertensive drug therapy.

Gene - 25 Feb 2013

Oliveira-Paula Gustavo H, Lacchini Riccardo, Coeli-Lacchini Fernanda B, Junior Heitor Moreno, Tanus-Santos Jose E

Abstract excerpt

Hypertension is a multifactorial disorder associated with increased inducible nitric oxide synthase (iNOS) expression and activity. While genetic polymorphisms affect iNOS expression, it is not known whether iNOS gene polymorphisms affect the susceptibility to hypertension and the responses to antihypertensive therapy. This study aimed at assessing whether iNOS polymorphisms ((CCTTT)(n), g.-1026C>A, and...

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Identifiers

PMID: 23266817
DOI: 10.1016/j.gene.2012.12.059

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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