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Research on gene editing and immunosuppressants in kidney xenotransplantation

1 Feb 2025

Abstract excerpt

Gene-edited pig organ transplantation can solve the serious shortage of human donor organs. Currently, xenotransplantation is rapidly developing and has made significant breakthroughs. The use of GTKO (Gal knockout) pigs is an important step forward. The subsequent knockout of three genes combined with the transfer of immune-related genes effectively prolonged the survival time of non-human primate (NHP)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39900229
DOI: 10.1016/j.trim.2025.102184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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