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Article

LIS1, a glyco-humanized swine polyclonal anti-lymphocyte globulin, as a novel induction treatment in solid organ transplantation

2022-09-11

Abstract excerpt

<h4>ABSTRACT</h4> Anti-thymocyte/lymphocyte globulins (ATGs/ALGs) are immunosuppressive drugs used in induction therapies to prevent acute rejection in solid organ transplantation. Because of animal origin, ATGs/ALGs contain highly immunogenic carbohydrate xenoantigens eliciting antibodies that are associated with subclinical inflammatory events possibly impacting long-term graft survival. Their strong and long-l...

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Literature Corpus work
0796129a-24d5-56a5-b58e-e7e5bb6cfe1e
DOI
10.1101/2022.09.08.507114
Open publication

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