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Article

Direct killing of xenograft cells by CD8+ T cells of discordant xenograft recipients.

Transplantation - 15 Dec 2002

Tanemura Masahiro, Chong Anita S, DiSesa Verdi J, Galili Uri

Abstract excerpt

BACKGROUND: Long-term pig xenografts in monkeys demonstrated the infiltration of CD8 T cells into pig cartilage xenografts, transplanted into monkeys. The objective of the present study was to determine in an experimental animal model whether CD8 T cells in pig xenograft recipients exert any direct cytotoxic effect on pig cells. METHODS: The killing of xenograft cells by CD8 T cells, obtained from xenograft...

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Source

Identifiers

PMID: 12490793
DOI: 10.1097/00007890-200212150-00017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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