Article
Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors.
Cancer research - 1 Nov 2006
Marsit Carmen J, Houseman E Andres, Christensen Brock C, Eddy Karen, Bueno Raphael, Sugarbaker David J, Nelson Heather H, Karagas Margaret R, Kelsey Karl T
Abstract excerpt
The CpG island methylator phenotype (CIMP), thoroughly described in colorectal cancer and to a lesser extent in other solid tumors, is important in understanding epigenetics in carcinogenesis and may be clinically useful for classification of neoplastic disease. Therefore, we investigated whether...
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