Article
Janus model of the Na,K-ATPase beta-subunit transmembrane domain: distinct faces mediate alpha/beta assembly and beta-beta homo-oligomerization.
Journal of molecular biology - 19 Jan 2007
Barwe Sonali P, Kim Sanguk, Rajasekaran Sigrid A, Bowie James U, Rajasekaran Ayyappan K
Abstract excerpt
Na,K-ATPase is a hetero-oligomer of alpha and beta-subunits. The Na,K-ATPase beta-subunit (Na,K-beta) is involved in both the regulation of ion transport activity, and in cell-cell adhesion. By structure prediction and evolutionary analysis, we identified two distinct faces on the Na,K-beta trans...
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