Article
Structural and functional interaction sites between Na,K-ATPase and FXYD proteins.
The Journal of biological chemistry - 10 Sept 2004
Li Ciming, Grosdidier Aurelien, Crambert Gilles, Horisberger Jean-Daniel, Michielin Olivier, Geering Käthi
Abstract excerpt
Several members of the FXYD protein family are tissue-specific regulators of Na,K-ATPase that produce distinct effects on its apparent K(+) and Na(+) affinity. Little is known about the interaction sites between the Na,K-ATPase alpha subunit and FXYD proteins that mediate the efficient association and/or the functional effects of FXYD proteins. In this study, we have analyzed the role of the transmembrane segment...
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