Article
The contribution of apolipoprotein E alleles on cognitive performance and dynamic neural activity over six decades.
Biological psychology - 1 Jul 2007
Alexander D M, Williams L M, Gatt J M, Dobson-Stone C, Kuan S A, Todd E G, Schofield P R, Cooper N J, Gordon E
Abstract excerpt
Neuroimaging shows brain-functional differences due to apolipoprotein E (APOE) polymorphisms may exist decades before the increased risk period for Alzheimer's disease, but little is known about their effect on cognition and brain function in children and young adults. This study assessed 415 healthy epsilon2 and epsilon4 carriers and matched epsilon3/epsilon3 controls, spanning ages 6-65, on a range of cognitive...
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