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Article

Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2006

Labelle-Dumais Cassandre, Jacob-Wagner Mariève, Paré Jean-Francois, Bélanger Luc, Dufort Daniel

Abstract excerpt

NR5A2, also known as liver receptor homologue 1 (LRH-1) and fetoprotein transcription factor (FTF), is an orphan nuclear receptor involved in the regulation of cholesterol metabolism and steroidogenesis in the adult. NR5A2 was also shown to be expressed during early mouse embryogenesis. Consistent with its early expression pattern, a targeted disruption of this gene leads to embryonic lethality around the...

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PMID: 17075876
DOI: 10.1002/dvdy.20996

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GATA4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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