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A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafish

2024-03-14

Abstract excerpt

Nr2f transcription factors (TFs) are conserved regulators of vertebrate atrial cardiomyocyte (AC) differentiation. However, little is known about the mechanisms directing Nr2f expression in ACs. Here, we identified a conserved enhancer 3’ to the nr2f1a locus, which we call 3’reg1-nr2f1a ( 3’reg1 ), that can promote Nr2f1a expression in ACs. Sequence analysis of the enhancer identified putative Lef/Tcf and Foxf...

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Literature Corpus work
44c7c6fb-eb24-5627-b670-a35173d5280a
DOI
10.1101/2024.03.13.584759
Open publication

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A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafishDOI 10.1101/2024.03.13.584759
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