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Article

Development of leiomyosarcoma of the uterus in MMTV‐CR‐1 transgenic mice

27 Oct 2006

Abstract excerpt

Overexpression of Cripto-1 (CR-1) in FVB/N mice using the MMTV-LTR promoter results in increased mammary tumourigenesis in these female transgenic mice (MMTV-CR-1). Here, we characterize uterine tumours that developed in 15/76 (19.7%) of MMTV-CR-1 female nulliparous or multiparous mice during 24 months of observation compared with 0/33 (0%) of FVB/N normal control mice observed during the same time period (p <...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17072826
DOI: 10.1002/path.2083

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