Article
Positional cloning: complex cardiovascular traits.
Methods in molecular medicine - 1 Jan 2006
Gulcher Jeffery, Stefansson Kari
Abstract excerpt
Cardiovascular traits represent the quintessential complex trait derived from the confluence of numerous genetic and environmental risk factors. Therefore, positional cloning of cardiovascular genes contributing to the common forms of cardiovascular disease is much more challenging than the mapping and isolation of genes contributing to rare Mendelian phenocopies of cardiovascular disease. Success requires...
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