Article
New genetic concepts in hypertensive cardiovascular disease.
Current opinion in cardiology - 1 Sept 1998
Dominiczak A F, Jeffs B, Connell J M
Abstract excerpt
Hypertension is a complex quantitative trait under polygenic control. The identification of genes responsible for high blood pressure is of major importance, because it provides a mechanistic classification of the common phenotype and guide therapy tailored to the underlying primary abnormality....
Topics
- Animals
- Blood Pressure
- Cardiovascular Diseases
- Chromosomes
- Disease Models, Animal
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Linkage Disequilibrium
- Mutation
- Quantitative Trait, Heritable
- Rats
- Rats, Inbred Strains
