Article
Genetic epidemiology, genetic maps and positional cloning.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Oct 2003
Morton Newton E
Abstract excerpt
Genetic epidemiology developed in the middle of the last century, focused on inherited causes of disease but with methods and results applicable to other traits and even forensics. Early success with linkage led to the localization of genes contributing to disease, and ultimately to the Human Genome Project. The discovery of millions of DNA markers has encouraged more efficient positional cloning by linkage...
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