Article
Integration--a key to success in the genetic dissection of complex diseases?
Trends in cardiovascular medicine - 1 Feb 2006
Yagil Yoram, Yagil Chana
Abstract excerpt
Complex diseases are polygenic and multifactorial. The outcome of two decades of search for the culprit genes in complex diseases involving the cardiovascular system has been less than satisfactory. Genomic studies using linkage analysis have led so far to the detection of a large number of quantitative trait loci that embed a large number of candidate genes. Transcriptomic studies using differential gene...
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