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Article

The C/A(-18) polymorphism in the surfactant protein B gene influences transcription and protein levels of surfactant protein B.

American journal of physiology. Lung cellular and molecular physiology - 1 Feb 2007

Steagall Wendy K, Lin Jing-Ping, Moss Joel

Abstract excerpt

Surfactant protein B (SP-B) is an essential component of surfactant that promotes adsorption and spreading of surfactant phospholipids and stabilizes the phospholipid monolayer. SP-B is essential for respiratory function in newborn humans and mice; adult mice with levels of SP-B below 25% of wild-type develop fatal respiratory distress syndrome. A potential regulatory function of the C/A(-18) single nucleotide...

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Identifiers

PMID: 17071721
DOI: 10.1152/ajplung.00307.2006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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