Article
Surfactant proteins in pediatric interstitial lung disease.
Pediatric research - 1 Jan 2016
Griese Matthias, Lorenz Elke, Hengst Meike, Schams Andrea, Wesselak Traudl, Rauch Daniela, Wittmann Thomas, Kirchberger Valerie, Escribano Amparo, Schaible Thomas, Baden Winfried, Schulze Johannes, Krude Heiko, Aslanidis Charalampos, Schwerk Nicolaus, Kappler Matthias, Hartl Dominik, Lohse Peter, Zarbock Ralf
Abstract excerpt
BACKGROUND: Children's interstitial lung diseases (chILD) comprise a broad spectrum of diseases. Besides the genetically defined surfactant dysfunction disorders, most entities pathologically involve the alveolar surfactant region, possibly affecting the surfactant proteins SP-B and SP-C. Therefore, our objective was to determine the value of quantitation of SP-B and SP-C levels in bronchoalveolar lavage fluid...
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