Article
Binding hot spots in the TEM1-BLIP interface in light of its modular architecture.
Journal of molecular biology - 19 Jan 2007
Reichmann D, Cohen M, Abramovich R, Dym O, Lim D, Strynadka N C J, Schreiber G
Abstract excerpt
Proteins bind one another in aqua's solution to form tight and specific complexes. Previously we have shown that this is achieved through the modular architecture of the interaction network formed by the interface residues, where tight cooperative interactions are found within modules but not bet...
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