Article
Mutual regulation of conventional protein kinase C and a ubiquitin ligase complex.
Biochemical and biophysical research communications - 15 Dec 2006
Nakamura Munehiro, Tokunaga Fuminori, Sakata Shin-ichi, Iwai Kazuhiro
Abstract excerpt
Several isoforms of protein kinase C (PKC) are degraded by the ubiquitin-proteasome pathway after phorbol ester-mediated activation. However, little is known about the ubiquitin ligase (E3) that targets activated PKCs. We recently showed that an E3 complex composed of HOIL-1L and HOIP (LUBAC) gen...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
