Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MZF-1/Elk-1/PKCα is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma

1 Jan 2017

Abstract excerpt

Background: Protein kinase C alpha (PKC) is a key signaling molecule in human cancer development. As a therapeutic strategy, targeting PKC is difficult because the molecule is ubiquitously expressed in non-malignant cells. PKC is regulated by the cooperative interaction of the transcription factors myeloid zinc finger 1 (MZF-1) and Ets-like protein-1 (Elk-1) in human cancer cells. Methods: By conducting tissue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to FOXO transcription factor regulation
Share to Mechanisms of cancer metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28928894
DOI: 10.7150/jca.20467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MZF-1/Elk-1/PKCα is Associated with Poor Prognosis in Patients with Hepatocellular CarcinomaPMID 28928894Read ↗

The complexities of PKCα signaling in cancer.Semantic proximity Read ↗

Pan-Cancer Study on Protein Kinase C Family as a Potential Biomarker for the Tumors Immune Landscape and the Response to ImmunotherapySemantic proximity Read ↗

DNA-PKcs: A Targetable Protumorigenic Protein KinaseSemantic proximity Read ↗

The Emerging Function of PKCtheta in CancerSemantic proximity Read ↗

Protein Kinase C at the Crossroad of Mutations, Cancer, Targeted Therapy and Immune ResponseSemantic proximity Read ↗

Integrative genomic analysis of protein kinase C (PKC) family identifies PKCiota as a biomarker and potential oncogene in ovarian carcinoma.Semantic proximity Read ↗

Protein Kinase C Alpha is a Central Node for Tumorigenic Transcriptional Networks in Human Prostate CancerSemantic proximity Read ↗

Protein Kinase C Alpha is a Central Node for Tumorigenic Transcriptional Networks in Human Prostate CancerSemantic proximity Read ↗

EGFR-induced and PKCε monoubiquitylation-dependent NF-κB activation upregulates PKM2 expression and promotes tumorigenesis.Semantic proximity Read ↗

DNA-PKcs: A promising therapeutic target in human hepatocellular carcinoma?Semantic proximity Read ↗

Quantification of <i>PKC</i> family genes in sporadic breast cancer by qRT‐PCR: Evidence that <i>PKC</i>ι/λ overexpression is an independent prognostic factorSemantic proximity Read ↗

PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.