Article
Association of frequent consumption of fatty fish with prostate cancer risk is modified by COX-2 polymorphism.
International journal of cancer - 15 Jan 2007
Hedelin Maria, Chang Ellen T, Wiklund Fredrik, Bellocco Rino, Klint Asa, Adolfsson Jan, Shahedi Katarina, Xu Jianfeng, Adami Hans-Olov, Grönberg Henrik, Bälter Katarina Augustsson
Abstract excerpt
Dietary intake of marine fatty acids from fish may protect against prostate cancer development. We studied this association and whether it is modified by genetic variation in cyclooxygenase (COX)-2, a key enzyme in fatty acid metabolism and inflammation. We assessed dietary intake of fish among 1,499 incident prostate cancer cases and 1,130 population controls in Sweden. Five single nucleotide polymorphisms...
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