Article
Association analysis of the PTPN22 gene in childhood-onset systemic lupus erythematosus in Mexican population.
Genes and immunity - 1 Dec 2006
Baca V, Velázquez-Cruz R, Salas-Martínez G, Espinosa-Rosales F, Saldaña-Alvarez Y, Orozco L
Abstract excerpt
Several studies have identified a functional single nucleotide polymorphism 1858C/T in the PTPN22 gene to be associated with several autoimmune diseases. Association studies of this polymorphism with familial and sporadic systemic lupus erythematosus (SLE) have shown some discrepancies. To our knowledge, this is the first study that includes only pediatric-onset SLE patients. We performed a case-control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
